BRIMONIDINE (bri-MOE-ni-deen)+TIMOLOL (TIM-oh-lole)

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Quantity Strength Unit Price Price Cart
1 Bottle Combigan Solution 0.2-0.5 5ml Bottle $19.19 $19.19
3 Bottle Combigan Solution 0.2-0.5 5ml Bottle $18.80 $56.39


What is the brief overview about Combigan eye drops?

Combigan eye drop is the drug that is classified in the class of drugs used to treat open-angle glaucoma conditions in the eye. Open-angle glaucoma is another common eye disorder that can even lead to worsening eye condition i.e. blindness. This condition affects the optic nerve of the eye and damages it after certain time being suffering from open-angle glaucoma. Glaucoma is the result of the condition of increased fluid pressure in the eye making the eye unable to form clear images. This disorder is to be treated before it becomes worsens.

What is the mechanism of Action followed by the Combigan drug?

Combigan eye drop is a combination of two drugs including Brimonidine tartrate and Timolol maleate.

Brimonidine falls in the category of drugs alpha-adrenergic receptor agonist. Brimonidine has a dual mechanism of action on the condition of open-angle glaucoma condition as it reduces both aqueous humor production and increases uveoscleral outflow.

Timolol is supposed to compete with adrenergic neuro transmitters Catecholamine, forms a complex with beta-1 and beta-2 receptors, and decreases the secretion of aqueous humor in the eye. This reduces the ocular pressure in the eye and giving relief in open-angle glaucoma condition.

What is suitable dosing scheme for Combigan eye drops?

In 1 ml of Combigan eye drop, 2mg of Brimonidine tartrate and 1 mg of Timolol is present. The dose suggested for Combigan eye drop is one drop instilled in the infected eye for about two times in the day keeping a gap of 12 hours apart.

Which contradictory conditions are to be kept in mind with Combigan eye drops?

• Any one should not use Combigan eye drop if he is allergic to any of the component of the drug.
• The person with a history of asthma or chronic obstructive pulmonary disease (COPD) should not make the use of Combigan drops for his glaucoma condition.
• The person having any cardiovascular disorder like heart failure, slow heartbeats should not use Combigan medicine.

What should be the preventive tips with Combigan eye drops?

• The children under the age of 2 years are not supposed to give the medication with Combigan eye drops.
• The person should not use Combigan eye drops without removing contact lenses.
• Do consult the doctor about your eye injury or infection before using Combigan eye drops.
• The woman on her lactation period should avoid the use of Combigan eye drop.
• A pregnant woman should always consult her doctor before relying on Combigan eye drops.
• Do not use any other eye drops for any purpose along with Combigan eye drops.
• As soon as the eye drops are instilled, one should avoid doing tasks that need proper alertness.

What are the side issues observed with Combigan eye drops?

Some of the common side issues that a person could experience with the use of Combigan medicine include drowsiness, dizziness, mild itching, redness, itching in the eye, mild stinging, or sensation of foreign particles in the eyes.

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