CLOMIPRAMINE-(kloe mi pra meen)

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Generic Anafranil is used to treat depression, narcolepsy (muscle weakness in people with a sleep disorder), and obsessive compulsive disorder. It belongs to the class of medicine known as tricyclic anti-depressant. This drug acts by increasing the activity of serotonin, a chemical neurotransmitter used by neurons to communicate with each other. It is recommended to take, for the treatment of depression, obsessive-compulsive disorders (50 to 75 mg) in a day, for the treatment of narcolepsy (25 to 75 mg) each day with or without food.

Quantity Strength Unit Price Price Cart
30 Tab Anafranil 10mg - Generic $0.22 $6.60
90 Tab Anafranil 10mg - Generic $0.20 $18.00
30 Tab Anafranil 25mg - Generic $0.34 $10.20
90 Tab Anafranil 25mg - Generic $0.33 $29.40
30 Tab Anafranil 50mg - Generic $0.50 $15.00
90 Tab Anafranil 50mg - Generic $0.50 $45.00
30 Tab Anafranil 75mg SR - Generic $0.68 $20.40
90 Tab Anafranil 75mg SR - Generic $0.67 $60.60


In Anafranil, active drug is clomipramine hydrobromide. It belongs to the antidepressant class of tricyclic antidepressants .It inhibits the absorption of reuptake of neurotransmitter serotonin. According to the experts, imbalance of neurotransmitter in the body is responsible for causing depression.


 Generic Anafranil is used to treat depression, narcolepsy (muscle weakness in people with a sleep disorder), and obsessive compulsive disorder. 


The use of this drug is contraindicated in certain condition

  • In case of any sensitivity to analafril or any of its ingredients
  • In case of recovery from any heart disease
  • In case of taking another anti-depressant such as monoamine oxidase inhibitor (MAOI), or have taken an MAOI within the last 14 days. 

Drug interactions:

 Some drugs that might interact with generic Anafranil such as:

  •  Avoid intake of MAOI medicines such as isocarboxide
  • Avoid intake of medicines e.g. warfarin to prevent blood clots
  • Avoid intake of diuretic medicines, also called fluid or water tablets
  • Avoid intake of NSAIDs such as ibuprofen it increases the risk of bleeding.
  • Avoid intake of other medicines for depression called SSRIs or SNaRIs (e.g. fluoxetine, paroxetine, sertraline, fluvoxamine)
  • Avoid intake of medicines for other mental disorders


  • It should be stored at room temperature in a range of 15-30 degree centigrade.
  • It should be kept away from the reach of children and pets. 


Swallow the tablets with a full glass of water. To avoid stomach discomfort, take it with a meal or after a snack.

In adults, for the treatment of depression, obsessive-compulsive disorders, treatment is usually started with a low dose of (50 to 75 mg) in a day.

For muscle weakness accompanying narcolepsy, the dose is usually from 1 to 3 tablets (25 to 75 mg) each day.

It usually takes 4-6 weeks for complete improvement.

What you do in case of Missed dose of Anafranil?

 If you misses your dose, and then you should take it as soon as you remember about it. However if it is time for next dose then take the regular dose scheduled and skip the missed dose. Do not take extra medicine to make up for missed dose.

What you do in case of overdose of Anafranil?

Overdose symptoms include agitated, sleepy, , muscle rigidity, difficulty in muscle movements, a falling blood pressure, fever, sweating, vomiting, breathing problem, irregular heartbeat, fits. An accidental overdose is especially dangerous. 

Side effects

Some common side effects include poor appetite or weight loss nausea (feeling sick), vomiting, diarrhea, disturbed sleep or nightmares,  feeling of unrest or anxiety repetitive, involuntary, purposeless movements, tired feeling and mental dullness decreased hunger, shakiness or tremble Some serious side effects include anxiety, depression, problems in speech, feeling sick, difficulty in urination, agitation, aggression, swelling hands, ankles, feet, blurred vision .


  • Do not share your drug with others.
  • Wear protective clothes of sun cream while going outside. This drug makes the skin more sun sensitive.
  • If this medicine makes you feel fainted, be careful when getting up from a sitting or lying position.
  • Avoid intake of grapefruit/grapefruit juice
  • Avoid intake of alcohol or driving because this drug leads to drowsiness.
  • Avoid driving or any machinery work, because this drug make you dizziness

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